https://www.ceesdekker.net - An Overview

‘Certainly, which is about ideal. I seek out a Actual physical comprehension of Organic methods in the base-up way. I think you might distinguish a few lines of analysis in my team in the mean time. The main issues chromosome framework: How does one get a metre-extended DNA polymer folded and organised in this type of microscopic cell? We've got formulated visualisation techniques that permit us to review how, such as, SMC proteins loop DNA (video on Youtube) as a way to Create up chromosomes.

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, Groningen researchers present the outcome of their attempts to generate labs additional sustainable and provide tricks for other labs. 

Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.

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Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: rapid electron relay to redox enzymes and zeptomole protein-film voltammetry

‘To start with we checked out Organic techniques that has a Actual physical see and acted on The idea of your resources we understood. It took a several years before we started out Performing extra on the big biological concerns. I then began to simply call it nanobiology, a time period that did not exist at the time.

2011, very first in vitro measurements of transport across only one biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the mechanism of homology recognition in DNA homologous recombination

The rotors harness Electrical power from a nanoscale water and ion move that is certainly generated by a static chemical or electrochemical opportunity gradient from the nanopore, which can be established via a salt gradient or utilized voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological ailments, suggesting approaches to constructing Strength-transducing motors at nanoscale interfaces.

It was throughout this period that Dekker carried out analysis on magnetic spin programs and on sounds in superconductors and semiconductors.

In 1993 he was appointed as Associate Professor at Delft College of Technology. Inside the mid-nineteen nineties Dekker and his team attained results with the invention from the electronic Houses of carbon nanotubes, the first single-molecule transistor and also other nanoscience.

‘That fears the synthetic cell, as Element of the Dutch BaSyC initiative. Craig Venter looked top rated-down in These days and discovered about five hundred genes which might be minimally demanded to get a operating mobile. We want to search base-up: how can we move from a several molecules to a complete biological technique?

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes

Sound-condition nanopores have established being a shockingly multipurpose probe for one-molecule cees dekker Assessment of DNA. I'll describe some of our recent conclusions – specifically DNA knots – as well as our efforts to expand the abilities of solid-point out nanopores even further more, during the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.